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OBJECTIVES@#To describe the clinical characteristics and outcomes of severely ill patients with coronavirus disease 2019, and to investigate the relationship between plasma glucose level and the prognosis of severely ill patients with coronavirus disease 2019.@*METHODS@#We enrolled 52 severely ill patients with coronavirus disease 2019. Among them, 12 cases progressed to critical illness. The clinical and biochemical characteristics of severely and critically ill patients were compared.@*RESULTS@#Compared with the severely ill patients, critically ill patients had higher white blood cell and neutrophil counts, as well as higher levels of -dimer, IL-6 and C-reactive protein (all <0.05). Before treatment, the fasting plasma glucose (FPG) levels were significantly higher in the critically ill patient's group [(10.23±3.71) mmol/L] compared to those in the severely ill patients [(7.12±3.35) mmol/L, <0.05]. After adjusting for age, gender, and course of the disease, fasting blood glucose at admission (OR=1.308, 95% CI 1.066 to 1.606, =0.01) and hyperglycemia at admission (OR=29.198, 95% CI 2.903 to 293.639, =0.004) were closely related to whether severely ill patients progressed to critical patients with coronavirus disease 2019. In our study, 15 (34.8%) of the severely ill and 10 (83.3%) critically ill patients received the steroid treatment. Compared with the severely ill patients, the FPG levels in critically ill patients were higher (<0.05).@*CONCLUSIONS@#Fasting hyperglycemia at admission is a significant predictor for the prognosis of severely ill patients with coronavirus disease 2019. Closely monitoring and the optimal management of hyperglycemia may improve the prognosis of patients with coronavirus disease 2019.
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Humans , Betacoronavirus , Blood Glucose , Coronavirus Infections , Blood , Diagnosis , Critical Illness , Hyperglycemia , Leukocyte Count , Pandemics , Pneumonia, Viral , Blood , Diagnosis , PrognosisABSTRACT
Objective@#To explore the mediating, direct and indirect roles of self-efficacy, social support and medical coping modes with resilience in patients with chronic hepatitis B.@*Methods@#Totally 384 inpatients and outpatients with chronic hepatitis B, without physical ailments or mental problems were selected.The Connor-Davidson resilience scale (CD-RISC), general self-efficacy scale (GSES), medical coping modes questionnaire (MCMQ) and social support rating scale (SSRS) were adopted in this research.The relationship among all variables was explored by path analysis.@*Results@#(1)The total scores of resilience, self-efficacy, social support, confrontation, avoidance and acceptance-resignation in chronic hepatitis B patients were (61.64±15.36), (25.40±5.70), (39.82±7.39), (19.02±3.72), (16.63±2.69) and (8.45±2.94), respectively.(2)Pearson analysis showed that the scores of self-efficacy, medical coping and social support were significantly correlated with resilience(r=-0.26-0.82, P<0.05). (3)Importantly, path analysis showed that self-efficacy(β=0.53), confrontation(β=0.10), avoidance(β=0.17) and acceptance-resignation(β=-0.13) had direct prediction effects on resilience.Additionally, self-efficacy was indirectly related to resilience(β=0.05), and social support also indirectly related to resilience through self-efficacy, confrontation and acceptance-resignation(β=0.18).@*Conclusion@#Self-efficacy, social support and medical coping are the important factors which play a direct or indirect role in resilience.
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Objective To explore the mediating,direct and indirect roles of self-efficacy,social support and medical coping modes with resilience in patients with chronic hepatitis B.Methods Totally 384 inpatients and outpatients with chronic hepatitis B,without physical ailments or mental problems were selected.The Connor-Davidson resilience scale (CD-RISC),general self-efficacy scale (GSES),medical coping modes questionnaire (MCMQ) and social support rating scale (SSRS) were adopted in this research.The relationship among all variables was explored by path analysis.Results (1)The total scores of resilience,self-efficacy,social support,confrontation,avoidance and acceptance-resignation in chronic hepatitis B patients were (61.64± 15.36),(25.40±5.70),(39.82±7.39),(19.02±3.72),(16.63 ±2.69) and (8.45 ±2.94),respectively.(2)Pearson analysis showed that the scores of self-efficacy,medical coping and social support were significantly correlated with resilience (r=-0.26-0.82,P＜0.05).(3) Importantly,path analysis showed that self-efficacy(β=0.53),confrontation (β=0.10),avoidance (β3=0.17) and acceptance-resignation (β=-0.13) had direct prediction effects on resilience.Additionally,self-efficacy was indirectly related to resilience(β3=0.05),and social support also indirectly related to resilience through self-efficacy,confrontation and acceptance-resignation (β=0.18).Conclusion Self-efficacy,social support and medical coping are the important factors which play a direct or indirect role in resilience.
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OBJECTIVE@#To establish an interference mode of group counseling for diabetic patients with depression and to evaluate the effectiveness of this mode on depression, treatment compliance and blood sugar level in the patients. @*METHODS@#One hundred diabetic patients with depression were randomly divided into a counseling group and a control group (n=50 per group). Self-Rating Depression Scale (SDS) was applied to all the patients. The interference mode of group counseling was established through literature review, expert consultation or interview. The counseling group received counseling for 8 times within 2 months. @*RESULTS@#There was a significant difference in the SDS scores at 0, 3, 6 or 12 months after the intervention between the 2 groups (P0.05). There was a significant difference in the compliance between any two time points after the intervention (P<0.05). Fasting blood glucose (FBG), 2 h postprandial blood glucose (2hPG) or glycosylated hemoglobin (HbA1c) was significantly different at any two time points after the intervention (P<0.05). @*CONCLUSION@#Group counseling can improve depression, compliance and blood sugar control in the diabetic patients.